| Transactions | ||||||
| Date | Team | Player | Type | OthTm | EffDate | When |
| 1/17/2008 | EDH | Roberts | Signed | Before | ||
| 1/17/2008 | MA | Pena | Signed | Before | ||
| 1/23/2008 | SPS | Edmonds | Demoted to reserve roster | Before | ||
| 1/23/2008 | SPS | Gutierrez | Signed | Before | ||
| 1/30/2008 | MA | Bowen | Released | Before | ||
| 1/30/2008 | MA | Bowen | Released | Before | ||
| 1/30/2008 | MA | Bowen | Released | Before | ||
| 1/30/2008 | MA | Bowen | Signed | Before | ||
| 1/30/2008 | MA | Bowen | Signed | Before | ||
| 1/30/2008 | MA | Bowen | Signed | Before | ||
| 1/30/2008 | MA | Bowen | Signed | Before | ||
| 1/30/2008 | MA | Britton | Released | Before | ||
| 1/30/2008 | MA | Britton | Signed | Before | ||
| 1/30/2008 | MA | Delcarmen | Signed | Before | ||
| 1/30/2008 | MA | Lopez | Released | Before | ||
| 1/30/2008 | MA | Lopez | Signed | Before | ||
| 2/1/2008 | MA | Bowen | Released | Before | ||
| 2/1/2008 | MA | Bowen | Released | Before | ||
| 2/1/2008 | MA | Bowen | Released | Before | ||
| 2/1/2008 | MA | Bowen | Released | Before | ||
| 2/1/2008 | MA | Bowen | Signed | Before | ||
| 2/1/2008 | MA | Bowen | Signed | Before | ||
| 2/1/2008 | MA | Bowen | Signed | Before | ||
| 2/1/2008 | MA | Bowen | Signed | Before | ||
| 2/5/2008 | RWC | Ludwick | Signed | Before | ||
| 2/5/2008 | RWC | Villarreal | Signed | Before | ||
| 2/7/2008 | MJ | Cook | Signed | Before | ||
| 2/7/2008 | MJ | Paulino | Signed | Before | ||
| 2/7/2008 | MJ | Wuertz | Signed | Before | ||
| 2/11/2008 | MA | Bowen | Released | Before | ||
| 2/11/2008 | RWC | Reyes | Signed | Before | ||
| 2/11/2008 | RWC | Villarreal | Released | Before | ||
| 2/22/2008 | SPS | Traber | Signed | Before | ||
| 2/26/2008 | MA | Bowen | Released | Before | ||
| 2/26/2008 | MA | Bowen | Released | Before | ||
| 2/26/2008 | MA | Bowen | Released | Before | ||
| 2/26/2008 | MA | Bowen | Signed | Before | ||
| 2/26/2008 | MA | Bowen | Signed | Before | ||
| 2/26/2008 | MA | Bowen | Signed | Before | ||
| 2/26/2008 | MA | Bowen | Signed | Before | ||
| 3/2/2008 | MA | Delcarmen | Demoted to reserve roster | Before | ||
| 3/2/2008 | RWC | Gonzalez,Ed | Signed | Before | ||
| 3/2/2008 | RWC | Kuo | Signed | Before | ||
| 3/2/2008 | RWC | Kuo | Demoted to reserve roster | Before | ||
| 3/2/2008 | RWC | Ludwick | Demoted to reserve roster | Before | ||
| 3/2/2008 | SPS | Edmonds | Demoted to reserve roster | Before | ||
| 3/2/2008 | SPS | Edmonds | Promoted to active roster | Before | ||
| 3/2/2008 | SPS | Gutierrez | Demoted to reserve roster | Before | ||
| 3/3/2008 | RWC | Gonzalez,Ed | Demoted to reserve roster | Before | ||
| 3/3/2008 | RWC | Gonzalez,Ed | Promoted to active roster | Before | ||
| 3/3/2008 | RWC | Kuo | Demoted to reserve roster | Before | ||
| 3/3/2008 | RWC | Kuo | Promoted to active roster | Before | ||
| 3/3/2008 | RWC | Ludwick | Promoted to active roster | Before | ||
| 3/5/2008 | SPS | Gutierrez | Promoted to active roster | Before | ||
| 3/5/2008 | SPS | Peavy | Demoted to reserve roster | Before | ||
| 3/7/2008 | BBB | Roberts | Signed | Before | ||
| 3/7/2008 | MA | Bowen | Demoted to reserve roster | Before | ||
| 3/7/2008 | MA | Santana | Signed | Before | ||
| 3/7/2008 | MA | Wilson | Demoted to reserve roster | Before | ||
| 3/9/2008 | MA | Delcarmen | Promoted to active roster | Before | ||
| 3/9/2008 | MA | Santana | Demoted to reserve roster | Before | ||
| 3/9/2008 | MA | Wilson | Promoted to active roster | Before | ||
| 3/9/2008 | SPS | Gutierrez | Demoted to reserve roster | Before | ||
| 3/9/2008 | SPS | Peavy | Promoted to active roster | Before | ||
| 4/2/2008 | MA | Santana | Placed on disabled list | 3/21/2008 | Before | |
| 4/2/2008 | RWC | Gonzalez,Ed | Demoted to reserve roster | Before | ||
| 4/2/2008 | RWC | Reyes | Demoted to reserve roster | Before | ||